Fields of Research
- Neuronal cell biology
- Regulation of neurotransmitter release
- Lipid-based regulation of cellular processes
Research Summary
Determining how membrane proteins and lipids regulate the functioning of neurons.
Research Statement
We study how organelle membrane composition influences fundamental cellular processes. Our current work is focused on understanding how the composition of synaptic vesicle membranes modulates the release of neurotransmitter from neurons and how lipid modifying enzymes organize and regulate intracellular signaling.
Awards and Honors
N/A
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program
Faculty
- Building:
- Health Sciences Building K Wing
- Box:
- 357750
- Phone:
- 206-616-2962
- Web Link:
- http://depts.washington.edu/phcol/faculty/bajjalieh.php
Lab
- Building:
- Health Sciences Building K Wing
- Room:
- K516, K522
- Box:
- 357750
- Phone:
- 206-616-2963
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program
PHCOL402
PHCOL512
NEUBIO404
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program
N/A
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program
Select Publications
Nowack A, Malarkey EB, Yao J, Bleckert A, Hill J, Bajjalieh SM. (2011) Levetiracetam reverses synaptic deficits produced by overexpression of SV2A, PLoS One. 2011;6(12):e29560. Epub 2011 Dec 29
Yao J, Ong, S-E, Bajjalieh SM. (2014) Huntingtin is associated with cytomatrix proteins at the presynaptic terminal. Molecular and Cellular Neuroscience 63:96-100
Rosasco, MG, Gordon, SE, Bajjalieh, SM (2015) Characterization of the Functional Domains of a Mammalian Voltage-Sensitive Phosphatase, Biophysical Journal, 109:2480-91
Ciruelas, K, Marcotulli, D, and Bajjalieh, SM (2019) Synaptic Vesicle Protein 2: a multi-faceted regulator of secretion. Seminars in Cell and Developmental Biology
Sandra Bajjalieh
Professor
Affiliations
UW Molecular & Cellular Biology Graduate Program
UW Neuroscience Graduate Program
UW Biophysics, Structure, and Design Graduate Program