INTRACELLULAR
SIGNALING

Cells respond to their environment through the relay of chemical and electrical signals. Members of our department use molecular, genetic, and pharmacological tools to dissect these intracellular and organellar communication networks.

BROWSE OUR RESEARCH
DRUG DISCOVERY &
PRECISION MEDICINE GENE ARCHITECTURE
& ACTION INTRACELLULAR
SIGNALING MOLECULAR BASIS
OF DISEASE NEUROBIOLOGY
& BEHAVIOR PROTEIN
STRUCTURE

Gene Expression Changes by Morphine Withdrawal

Dr. John Neumaier

Numerous gene expression changes occur rapidly and dramatically after withdrawal from chronic Morphine use.

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The Membrane is the Message

Dr. Sandra Bajjalieh

The Bajjalieh Lab studies how the rare phospholipids regulate cellular functions such as exocytosis.

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GPCRS in Neural Circuits & Affective Behavior

Dr. Michael Bruchas

We develop pharmacological, optogenetic, genetic, imaging, and behavioral, approaches to study GPCR signaling in the nervous system.

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Signaling to the Powerhouse

Dr. Yasemin Sancak

The Sancak Lab studies how cells communicate with their mitochondria using calcium ion transport.

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Mapping Novel Kinase Substrates

Dr. Smita Yadav

The Yadav lab uses chemical genetics to discover the direct substrates of kinases in neurological disorders.

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