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A 3D molecular model showing interconnected protein structures in blue, green, red, and yellow on a dark background. The proteins are represented by ribbon diagrams, highlighting their complex shapes and connections.

PROTEIN
STRUCTURE

Understanding Pharmacology at the molecular level lies at the core of drug discovery. Members of our department use state-of-the-art structural and imaging techniques to develop novel therapeutics.

BROWSE OUR RESEARCH
DRUG DISCOVERY &
PRECISION MEDICINE GENE ARCHITECTURE
& ACTION INTRACELLULAR
SIGNALING MOLECULAR BASIS
OF DISEASE NEUROBIOLOGY
& BEHAVIOR PROTEIN
STRUCTURE
A smiling woman in a lab coat and gloves uses a pipette, standing in front of a molecular structure diagram with highlighted protein domains in various colors.

Structural Analysis of Transcription Factor Activity

Dr. Edith Wang

The Wang lab investigates the structural features of transcription factors important for the regulation of gene expression.

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Navigating Voltage-Gated Sodium Channels

Dr. William Catterall

Sodium and calcium channel proteins initiate chemical signaling in excitable cells.

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A scientific image shows colored molecular structures: two large green and blue complexes at the bottom, a yellow structure at the top, and a green and yellow complex in the center, all over a gray, blurry background.

EM Structural Analyses of Signaling Enzymes

Dr. John D.W. Scott

The Scott lab focuses on understanding the organization of signaling enzyme complexes using microscopic structural analytical methods.

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Biological Functions via Protein Interface

Dr. Ning Zheng

The Zheng lab probes how protein complexes and molecular interactions drive critical physiological processes in plants and animals.

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