Fields of Research
Neurobiology and behavior
Molecular basis of disease
Research Summary
We study the connectivity, physiology, and function of neural circuits that govern motivated behavior.
Research Statement
We are interested in the physiology and circuit connections that underlie the activity patterns and functions of neurons that regulate motivated behavior. We utilize a variety of techniques including patch clamp electrophysiology, gene manipulation with CRISPR/Cas9, fiber photometry, and optogenetics to ask questions about circuit connectivity, gene function, cellular physiology, and behavioral output.
Awards and Honors
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator
Faculty
- Building:
- Health Sciences Building
- Room:
- J-625
- Box:
- Box 357750
- Phone:
- 206-221-3631
- Web Link:
- https://www.sodenlab.org/
Lab
- Building:
- Health Sciences Building
- Room:
- J-631
- Box:
- Box 357750
- Phone:
- 206-221-3631
- Web Link:
- https://www.sodenlab.org/
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator
Postdoc: Siyi Ma
Graduate Sudent: Mary Loveless (Joint with Bruchas lab, Neuroscience graduate program)
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator
Select Publications
Simon RC, Loveless MC, Yee JX, Goh B, Cho SG, Nasir Z, Hashikawa K, Stuber GD, Zweifel LS, Soden ME. Opto-seq reveals input-specific immediate-early gene induction in ventral tegmental area cell types. Neuron. 2024 Aug 21;112(16):2721-2731.e5. doi: 10.1016/j.neuron.2024.05.026. Epub 2024 Jun 19. PubMed PMID: 38901431; PubMed Central PMCID: PMC11343674.
Soden ME, Yee JX, Zweifel LS. Circuit coordination of opposing neuropeptide and neurotransmitter signals. Nature. 2023 Jul;619(7969):332-337. doi: 10.1038/s41586-023-06246-7. Epub 2023 Jun 28. PubMed PMID: 37380765; PubMed Central PMCID: PMC10947507.
Yee JX, Rastani A, Soden ME. The potassium channel auxiliary subunit Kvβ2 (Kcnab2) regulates Kv1 channels and dopamine neuron firing. J Neurophysiol. 2022 Jul 1;128(1):62-72. doi: 10.1152/jn.00194.2022. Epub 2022 Jun 15. PubMed PMID: 35788155; PubMed Central PMCID: PMC9273274.
Publications
Marta
Assistant Professor
Affiliations
UW Nutritional and Obesity Research Center Affiliate Investigator