Fields of Research
- Precision medicine
- Gene architecture and action
- Molecular basis of disease
Research Summary
Technologies to discover epigenetic bases of disease
Research Statement
The Bomsztyk lab is developing high throughput technologies and computational tools to explore epigenetic bases of disease including cancer, organ injury and others. The goal is to use these user-friendly technologies to identify disease epigenetic alteration, biomarkers and druggable targets for precision medicine.
Awards and Honors
Established Investigatorship Award, American Heart Association
American Society Clinical Investigator
MERIT Award, NIH
Association of American Physicians
Co-founder Matchstick Technologies Inc. Kirkland WA
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH
Faculty
- Building:
- UW Medicine SLU
- Room:
- Brotman 243
- Box:
- 358050
- Phone:
- 206-616-7949
- Web Link:
- https://sites.uw.edu/bomsztyklab/
Lab
- Building:
- UW Medicine SLU
- Room:
- Brotman 242
- Box:
- 358050
- Phone:
- 205-543-1014
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH
PHCOL535
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH
Daniel Mar (Research Scientist II)
Oleg Denisenko (Research Professor)
Stephen Scheuerman (Research Engineer)
Mason Shaw (Research Engineer)
Andrea Lius (Student)
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH
Select Publications
Bomsztyk K, Mar D, Wang Y, Denisenko O, Ware C, Frazar CD, Blattler A, Maxwell AD, MacConaghy BE, Matula TJ: PIXUL-ChIP: integrated high-throughput sample preparation and analytical platform for epigenetic studies. Nucleic Acids Res. 47:e69, 2019
https://www.ncbi.nlm.nih.gov/pubmed/30927002
Sharifian R, Okamura DM, Denisenko O, Zager RA, Johnson A, Gharib SA, Bomsztyk K: Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury. Sci Rep 8:17870, 2018.
https://www.ncbi.nlm.nih.gov/pubmed/30552397
Karol Bomsztyk
Adjunct Professor
Affiliations
UW Molecular & Cellular Biology Training Program
UW Institute for Stem Cell & Regenerative Medicine
Attending Physician UWMC, Harborview and SCCA
Funding
NIH