Fields of Research
- Molecular Basis of Disease
- Neurobiology and Behavior
- Serotonin Pharmacology
My lab studies the molecular and cellular systems involved in stress and addiction.
My laboratory investigates the interface of pharmacology, molecular neuroscience, and behavior. We use strategies that span several levels of organization from RNA regulation, protein translation, cellular plasticity, and neural circuit level analysis of complex behaviors relating to stress and addiction models. We use rat and mouse behavioral models as well as in vitro cultures of cell lines and primary neurons to study components of intracellular signaling pathways.
Awards and Honors
Kevin Coffey, PhD
Jesse Kumar, MD, PhD
Katharine Liang, MD, PhD
Alec Gibson, BS
Marjorie Levinstein, BS, MS
Phillip Silva, BS
David Bergkamp, BS
Coffey, KR, Marx, RG, and Neumaier, JF. (2019). DeepSqueak: A Deep Learning Based System for Detection and Analysis of Ultrasonic Vocalizations. Neuropsychopharmacol, 44(5):859-868. PMID:30610191.
Liu, Y, Gibson, A, Levinstein, MR, Lesiak, AJ, Ong, S-E, and Neumaier, JF. (2019). Receptor-Mediated Activation of ERK1/2 Requires Both G.i/o and .-Arrestin Proteins. ACS Chem Neurosci. 10(7):3143-3153. PMID: 30946562.
Brodsky, M, Gibson, A, Smirnov, D, Nair, SG, and Neumaier JF. (2016). Striatal 5-HT6 receptors regulate cocaine reinforcement in a pathway-selective manner. Neuropsychopharmacol, 41:9:2377-87. PMCID: 4946068.
Lesiak, AJ, Brodsky, M, Cohenca, N, Croicu, AG, and Neumaier, JF. (2018). Restoration of physiological expression of 5-HT6 into the primary cilia of null mutant neurons lengthens both primary cilia and dendrites. Mol Pharm: 94(1):731-742. PMID:29678909.