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Hui Shi Profile
Fields of Research
- Molecular Basis of Disease
- Field
- Protein Structure
Research Summary
I use structural biology (cryo-EM and x-ray crystallography) techniques and biochemical approaches to study the ERAD pathway.
Research Statement
RING finger protein 139 (RNF139) is one of the components in the EARD pathway, whose malfunction is associated with cancers such as renal cell carcinoma. Uncovering how RNF139 regulates cellular homeostasis through the ERAD pathway in a molecular detail will provide us with valuable information for understanding its mechanism and will be beneficial to further studies, such as developing therapeutic strategies.
Awards and Honors
Why Pharmacology?
Contact Information
Faculty
- Building:
- Health Sciences Building
- Room:
- D408
- Phone:
- 206-616-3887
Lab
- Building:
- Health Sciences Building
- Room:
- D408
- Phone:
- 206-616-3887
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Students/Postdocs
Publications