GENE ARCHITECTURE
& ACTION

Since the discovery of the double helix, understanding gene architecture is a central tenet of biomedical research. Our faculty use cutting-edge “-omic” techniques to chart the intricate organization and action of genes.

BROWSE OUR RESEARCH
DRUG DISCOVERY &
PRECISION MEDICINE GENE ARCHITECTURE
& ACTION INTRACELLULAR
SIGNALING MOLECULAR BASIS
OF DISEASE NEUROBIOLOGY
& BEHAVIOR PROTEIN
STRUCTURE

A Close-up View of Chromatin-modifying Enzymes

Dr. Ning Zheng

The Zheng lab searches for therapeutic opportunities by delineating the architecture of enzymatic complexes writing, recognizing, and erasing various epigenetic marks.

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Unravelling the TFIID Protein Complex

Dr. Edith Wang

The Wang lab utilizes molecular, biochemical and structural approaches to study the TAF subunits of transcription factor IID complex in gene expression.

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Novel Regulators of Gene Expression

Dr. Shao-En Ong

The Ong lab studies how DNA-protein complexes regulate cellular differentiation with mass spectrometry proteomics.

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A Toolkit for Navigating the Modern RNA World

Dr. David Shechner

The Shechner lab develops novel chemical-biology technologies for probing the RNAs that organize subcellular architecture.

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