Fields of Research
- Molecular Basis of Disease
- Neurobiology and Behavior
- Protein Structure
Research Summary
Currently, my work in the Catterall lab explores the link between mutant voltage-gated ion channels and neurological disorders such as autism and epilepsy. In particular, I use in vitro electrophysiology to investigate pathological gating pore current in the voltage-gated potassium channel Kv7.3 and the voltage-gated sodium channel NaV1.2.
Research Statement
Autism spectrum disorder (ASD) is a neurological condition characterized by social skill impairments and repetitive behaviors. Recent literature has pointed to voltage-gated ion channels as frequent targets of de novo mutations that cause ASD. These mutations disproportionally target the residues forming the gating charges of the channels’ voltage sensors. Gating charge mutations are hypothesized to be pathogenic in ASD due to continuous sodium current leak and disruption of normal action potential firing patterns.
Awards and Honors
Recent Graduate B.S. Biology, B.A. Philosophy, University of Washington ’19
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology
Faculty
- Building:
- Health Sciences Building
- Room:
- F428
- Box:
- 357280
- Phone:
- (949) 726-2238
- Web Link:
- http://timothylantin.com/
Lab
- Building:
- Health Sciences Building
- Room:
- F428
- Box:
- 357280
- Phone:
- (206) 685-4588
- Web Link:
- https://depts.washington.edu/phcol/faculty/catterall.php
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology
Timothy Lantin
Research Scientist/Engineer 1
Affiliations
UW Department of Pharmacology