Profile
Contact Information
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Nicole Marsh Profile
Fields of Research
- Gene Architecture and Action
- Intracellular Signaling
- Molecular Basis of Disease
Research Summary
I investigate how the transcriptional and post-translational profile of the cell is altered to mitigate damage by environmental stresses.
Research Statement
When exposed to stress, cells must rapidly respond and adapt, or they risk suffering permanent damage. Post-translational modification of substrates by the protein SUMO (small ubiquitin-like modifier) is a critical signaling process across diverse cellular stress responses. I research how SUMOylation is regulated and its role in protecting DNA and modulating transcription during ethanol and heavy metal stresses.
Awards and Honors
Honorable mention – NSF Graduate Research Fellowship Program (GRFP), 2019
Why Pharmacology?
Contact Information
Faculty
- Building:
- Health Sciences Building
Lab
- Building:
- Health Sciences Building
- Phone:
- (206) 616-1976
- Web Link:
- https://gardnerlab.org/
Courses
Students/Postdocs
Publications